AffiPCR® Pneumocystis jirovecii (carinii) Real Time PCR

Target Disease Type: HIV Associated Kits

Specific Application: HIV Associated Kits

Storage and Shipping : stock

Pneumocystis jirovecii (carinii) RT-PCR (CE) P2-50FRT DataSheet

INTRODUCTION

Pneumocystis pneumonia (PCP) or pneumocystosis is a form of pneumonia, caused by the yeast-like fungus (which had previously been erroneously classified as a protozoan) Pneumocystis jirovecii (carinii) . P. jirovecii is now one of several organisms known to cause life-threatening opportunistic infections in patients with advanced HIV infection worldwide. An accurate diagnosis requires access to modern medical care not available worldwide. Currently, the frequency of documented Pneumocystis infection is increasing in Africa, with Pneumocystis organisms found in up to 80% on infants with pneumonia who have HIV infection.

INTENDED USE

The Pneumocystis jirovecii (carinii) Real-TM is a Real-Time test for the qualitative detection of Pneumocystis jirovecii (carinii) in biological materials.

PRINCIPLE OF ASSAY

Kit Pneumocystis jirovecii (carinii) Real – TM is based on two major processes: DNA extracted from samples and amplification using real time amplification with fluorescent reporter dye probes specific for Pneumocystis jirovecii (carinii) and Internal Control (IC) . Test contains an IC (β-globine gene) which serves as an amplification control for each individually processed specimen and to identify possible reaction inhibition.